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nitrofurantoin facts at Drugs.com

nitrofurantoin is used for:

Results of the sex-linked recessive lethal assay in Drosophila were negative after oral or parenteral administration of nitrofurantoin. However, all these reactions occur rarely and generally in those receiving nitrofurantoin therapy for 6 months or longer. Based on urinary pharmacokinetic data, the extent and rate of urinary excretion of nitrofurantoin from the 100 mg Macrobid capsule are similar to those of the 50 mg or 100 mg Macrodantin? (nitrofurantoin macrocrystals) capsule. {29}In subacute pulmonary reactions, recovery may require several months after termination of nitrofurantoin treatment. Lung papillary adenomas of unknown significance were observed in the F1 generation of pregnant mice given 75 mg per kg of body weight (mg/kg) of nitrofurantoin by subcutaneous injection.

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